Footnotes

• Contributors All authors contributed to the conception and writing of the manuscript. All authors reviewed and approved the submitted draft.

• Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

• Competing interests CR is a founder and Management Committee member of medRxiv.

• Patient consent for publication Not required.

• Provenance and peer review Not commissioned; internally peer reviewed.