Table 3 Univariate analyses for post-recurrence survival in 74 patients with resected stage I non-small cell lung cancer with local only recurrence
VariableHazard ratio (95% CI)p Value
Age at recurrence (years)1.007 (0.984 to 1.031)0.531
Gender (male vs female)1.519 (0.724 to 3.184)0.269
Smoking index (pack-years)1.001 (0.991 to 1.010)0.971
Location (right vs left lung)0.697 (0.419 to 1.159)0.697
Tumour size (cm)*1.132 (1.010 to 1.267)0.033
Histological type (squamous cell carcinoma vs others)0.840 (0.522 to 1.351)0.471
Extent of pulmonary resection (sublobar resection vs lobectomy or bilobectomy or pneumonectomy)1.644 (0.813 to 3.326)0.167
T status (T2 vs T1)1.220 (0.746 to 1.998)0.428
Visceral pleural invasion (present vs absent)0.932 (0.524 to 1.657)0.811
No of LNs dissected (>15 vs ⩽15)1.101 (0.644 to 1.884)0.725
Disease free interval (months) (>18 vs ⩽18)0.921 (0.573 to 1.482)0.736
Mediastinal recurrence (present vs absent)1.031 (0.969 to 1.097)0.335
Treatment for initial recurrence<0.001
    None1
    With surgery0.118 (0.035 to 0.400)
    C/T and/or R/T0.319 (0.134 to 0.763)
  • *The hazard ratio associated with tumour size is that the increase in hazard is associated with a 1 cm increase in tumour size.

  • C/T, chemotherapy; LN, lymph node; R/T, radiotherapy.