Key features of REMAP trials
| Key features | Description | |
| R | Randomised | Patients are randomised to all interventions for which they are eligible and consent to. |
| E | Embedded | The study protocol is embedded within routine clinical care, reflecting standard practice,and minimising additional study procedures. |
| M | Multifactorial | Multiple interventions (factors) are tested concurrently, with patients randomised to multiple treatment domains, increasing the probability of receiving at least one active treatment rather than control. |
| A | Adaptive | Information acquired during the trial is used to adaptively determine how the study should progress based on prespecified procedures in the protocol, such as a randomisation algorithm to determine randomisation weights to factors and stopping rules defining early success or futility. |
| P | Platform | A perennial infrastructure is developed with the objective to generate a continuous learning system. |