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Interferon gamma therapy and pulmonary fibrosis
  1. A R L Medford
  1. Clinical Research Fellow and Honorary Specialist Registrar, University of Bristol, Southmead Hospital, Bristol, UK; andrew.medford@bristol.ac.uk

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In this double blind multinational study, 330 patients with idiopathic pulmonary fibrosis were randomly assigned to treatment with either subcutaneous interferon gamma-1b (n = 162) or placebo (n = 168) three times daily for 48 weeks. Interferon gamma-1b had no significant effect on the primary end point (disease progression or death) compared with placebo. 10% …

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